Research links recreational pool disinfectants to health problems

Splashing around in a swimming pool on a hot summer day may not be as safe as you think

A recent University of Illinois study links the application of disinfectants in recreational pools to previously published adverse health outcomes such as asthma and bladder cancer.

Each year, 339 million visits take place at pools and water parks across the United States. Not only is swimming fun, but it’s also the second most popular form of exercise in the country. Because of this, disinfection of recreational pools is critical to prevent outbreaks of infectious disease.

However, Michael Plewa, U of I professor of genetics, said negative outcomes can occur when disinfection byproducts form reactions with organic matter in pool water.

Pool water represents extreme cases of disinfection that differ from the disinfection of drinking water as pools are continuously exposed to disinfectants.

“All sources of water possess organic matter that comes from decaying leaves, microbes and other dead life forms,” Plewa said. “In addition to organic matter and disinfectants, pool waters contain sweat, hair, skin, urine, and consumer products such as cosmetics and sunscreens from swimmers.”

These consumer products are often nitrogen-rich, causing concern that they may contribute to the generation of nitrogenous disinfection byproducts, Plewa added. When mixed with disinfectants, these products may become chemically modified and converted into more toxic agents. These disinfection byproducts can mutate genes, induce birth defects, accelerate the aging process, cause respiratory ailments, and even induce cancer after long-term exposures. In this study, collections from public pools and a control sample of tap water were evaluated to identify recreational water conditions that could be harmful to your health.

A systematic mammalian cell genotoxicity analysis was used to compare the water samples. Plewa said this sensitive DNA technology examined genomic damage in mammalian cells, allowing researchers to investigate damage at the level of each nucleus within each cell.

The study compared different disinfection methods and environmental conditions. Results proved that all disinfected pool samples exhibited more genomic DNA damage than the source tap water, Plewa said.

“Care should be taken in selecting disinfectants to treat recreational pool water,” Plewa advised. “The data suggest that brominating agents should be avoided as disinfectants of recreational pool water. The best method to treat pool waters is a combination of UV treatment with chlorine as compared to chlorination alone.”

Plewa recommends that organic carbon be removed prior to disinfection when the pool water is being recycled.

Also, swimmers can help reduce the genotoxicity of pool water by showering before entering the water. Pool owners should also remind patrons about the potential harm caused by urinating in a pool. These simple steps can greatly reduce the precursors of toxic disinfection byproducts, Plewa said.

Literature: University of Illinois College of Agricultural, Consumer and Environmental Sciences, Research links recreational pool disinfectants to health problems, July 21, 2010

EPA conference calls for consideration of asthmatics

First Perfume and Fragrance- free Asthma Conference

The American Environmental Protection Agency is holding a large asthma conference from June 17-19, 2010, in Washington D.C.. For the first time ever, the EPA has a special conference feature which is to renounce fragrances and perfume. Thus, the EPA is sending a signal to indicate the fragrance issue and to provide participants with asthma, the possibility to participate at the 2010 National Asthma Forum. Fragrances are among the principle factors for asthma attacks.

Nearly 300 experts and leaders, whose work is to improve the living conditions of people with asthma, are taking part in this event. Primary decision makers of federal and state authorities, as well as those responsible for guidelines, managers of health authorities, scientists, physicians and leaders of self-help organizations are included in this group. Their goal is to design environments to assist in safe living for all asthmatics.

In order to allow all participants to take part in the conference, meaning a conference free of perfume, aftershave, hairspray, body lotion, fabric softener or scented deodorants, the federal agency sent out the following reminder online:

“Asthma-friendly environments are our business – Please help us to make this a fragrance-free event by using fragrance-free personal care products and avoid perfumes and other irritants.”

This is a very positive step by the EPA. They have removed the largest known barrier for asthmatics and chemically injured people this year for the 2010 National Asthma Forum. World leaders on every continent should incorporate this humanitarian example by the EPA , for those disabled with illnesses affecting the breathing and lung function throughout the world.

Author: Silvia K. Müller, CSN – Chemical Sensitivity Network, 17 June 2010

Translation: Thank’s to Christi Howarth

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New blood test for newborns to detect allergy risk

A simple blood test can now predict whether newborn babies are at high risk of developing allergies as they grow older, thanks to research involving the University of Adelaide.

Professor Tony Ferrante, an immunologist from SA Pathology and the Children’s Research Centre at the University of Adelaide, says the new marker may be the most significant breakthrough in allergy testing for some decades.

“A protein in the immune cells of newborns appears to hold the answer as to whether a baby will either be protected, or susceptible to the development of allergies later on,” Professor Ferrante says.

Amounts of the cell signalling protein, called protein kinase C zeta, are much lower in children at risk of allergies.

Professor Ferrante says the blood test is far more effective than previous indicators, such as a family’s clinical history, or measuring the allergy-inducing antibody IgE.

In collaboration with Professor Susan Prescott from the University of Western Australia and Princess Margaret Hospital for Children, Professor Ferrante’s research team has refined the new marker for allergy risk, originally discovered in 2007, but now modified to a simple and manageable blood test at birth.

The researchers are also looking at whether fish oil supplements given to both pregnant women and those who have just given birth can reduce the risks of the children developing allergies.

“There is evidence that the levels of this important protein increase with fish oil supplementation to protect against allergy development,” Professor Ferrante says.

Australia has one of the highest allergy rates in the world, with 40% of children now suffering from allergic diseases, including food allergies, eczema, asthma and hay fever. These conditions frequently persist into adulthood, placing a heavy burden on the healthcare system.

Literature: The University of Adelaide, New blood test for newborns to detect allergy risk, 21 May 2010

Breathe easy: A natural fruit compound may help asthma

A preliminary study by New Zealand company Plant & Food Research shows that natural chemicals from blackcurrants may help breathing in some types of asthma.

Researchers found a compound from a New Zealand blackcurrant may reduce lung inflammation with a multi-action assault in allergy-induced asthma. The compound was found in laboratory experiments to enhance the natural defence mechanisms in lung tissue by both suppressing inflammation-causing reactions and minimising inflammation.

The findings are published in the journal Molecular Nutrition and Food Research.

Fruit consumption has been shown to reduce symptoms in allergy-induced asthma yet this research is the first to give insights into the mechanism by which this may occur. The researchers identified that the component, epigallocatechin, reduced inflammation in lung tissue. Epigallocatechin is a known antioxidant and a major component of proanthocyanidins found in blackcurrants.

In the Plant & Food Research study, led by Dr Roger Hurst, cells from lung tissue were used to test the effects on the immune system of a proanthocyanidin rich extract, from blackcurrant cultivars grown in New Zealand.

When the lungs are exposed to allergens, the body’s natural response is to attack the perceived foreign body which in some individuals results in long-term inflammation. Selective compounds found in fruit and vegetables may work together with the body’s own natural defence mechanism to suppress long-term lung inflammation.

This study shows that epigallocatechin, from blackcurrants, works in conjunction with other natural immune responses that occur at the same time to reduce inflammation. These actions are distinct from the inflammation-reducing activity of another group of compounds, anthocycanins, which are also rich in blackcurrants. Anthocyanins are known for their antioxidant properties and, interestingly, have been shown by Dr Hurst’s research group to also influence inflammatory mechanisms and complement the body’s own natural immune responses. The research shows some compounds in fruit thought to promote health with their antioxidant activity are keeping us well by other means.

“To find natural compounds that potentially reduce lung inflammation and complement the body’s own immune response is an exciting breakthrough,” says Dr Hurst. “Should we discover more about how this works we may eventually develop foods containing these compounds that could provide more natural alternatives to assist conventional drug treatments for asthma and even other allergic re-actions.”

The study is part of Plant & Food Research’s Food Innovation science platform that focuses on discovering the natural goodness in fruit, vegetables, grains and seafood and using this knowledge to develop fresh whole foods, ingredients and food concepts. Dr Kieran Elborough GM Science Food Innovation says research is improving the understanding of food and its makeup, how it benefits us and the development of new value technologies, ingredients and products.

“Maintaining wellness in a natural way is a growing consumer trend that food companies recognise, “says Dr Elborough. “New Zealand is well known for its quality fresh produce and I am quietly confident our understanding of natural compounds in fruit, vegetables, grains and seafood has good potential for food and beverage companies.”

Literatur: New Zealand Institute for Plant and Food Research, Breathe easy: A natural fruit compound may help asthma, March 25, 2010.

Study finds dirty air in California causes millions worth of medical care each year

California’s dirty air caused more than $193 million in hospital-based medical care from 2005 to 2007 as people sought help for problems such as asthma and pneumonia that are triggered by elevated pollution levels, according to a new RAND Corporation study.

Researchers estimate that exposure to excessive levels of ozone and particulate pollution caused nearly 30,000 emergency room visits and hospital admissions over the study period. Public insurance programs were responsible for most of the costs, with Medicare and Medi- Cal covering more than two-thirds of the expenses, according to the report.

“California’s failure to meet air pollution standards causes a large amount of expensive hospital care,” said John Romley, lead author of the study and an economist at RAND, a nonprofit research organization. “The result is that insurance programs — both those run by the government and private payers — face higher costs because of California’s dirty air.”

While much work has been done previously to catalog the economic impact of air pollution across California, the RAND study is the first to quantify the cost of hospital-based medical care to various payers caused by the failure to meet federal clean air standards across the state. More people in California live in areas that do not meet federal clean air standards than in any other state.

Romley said the findings show that private insurers, employers and public insurance programs all have a financial stake in improving California’s air quality.

“These costs may not be the largest problem caused by dirty air, but our study provides more evidence about the impact that air pollution has on the state’s economy,” Romley said.

Researchers used records from air pollution agencies and hospitals to estimate how failing to meet federal and state standards for particulate matter and ozone would affect private and public insurer spending for hospital admissions for respiratory and cardiovascular causes, and emergency room visits for asthma throughout California from 2005-2007.

Researchers say the most common hospital-based medical care triggered by elevated air pollution levels are emergency room visits for asthma among children aged 17 and under, with more than 12,000 visits over the three-year study period.

The most costly conditions examined by researchers were hospital admissions triggered by air pollution for acute bronchitis, pneumonia and chronic obstructive pulmonary disease. Those conditions accounted for nearly one-third of the $193 million in health care spending documented over the study period.

Nearly three-quarters of the health events identified by researchers were triggered by high levels of fine particulate pollution — tiny pieces of soot that can lodge deep in lungs. The health events examined in the study were concentrated in the San Joaquin Valley and the four-county South Coast Air Basin.

The cost of treating health events caused by air pollution is equal to the expense of providing flu vaccines to 85 percent of California children under age 15, according to the report.

Researchers say their study provides a conservative estimate about the costs of medical care triggered by air pollution because it does not include outpatient care provided in clinics or medical offices. Details about that type of medical care are not routinely reported to state agencies and thus could not be analyzed.

The study also includes case studies of individual hospitals in Fresno, Lynwood, Palo Alto, Riverside and Sacramento. That analysis demonstrates that costs and types of illness reported vary by region.

To conduct the study, researchers used epidemiological studies that link elevated pollution levels to respiratory and cardiovascular illnesses, and compared that information to pollution levels measured across the state from 2005 to 2007 by various public agencies. Researchers also reviewed detailed records hospitals report to the state about the patients they treat, the illnesses diagnosed and who pays for that care.

Literature:

RAND Corporation*, Study finds dirty air in California causes millions worth of medical care each year, March 2, 2010

*The RAND Corporation is a nonprofit research organization providing objective analysis and effective solutions that address the challenges facing the public and private sectors around the world.