Archive for category ‘Fibromyalgia‘

Electromagnetic Hypersensitivity and Multiple Chemical Sensitivity: two sides of the same coin?

In several countries EHS, MCS and fibromyalgia are already classified as functional disabilities

Several experts from different European countries agree that Electromagnetic Hypersensitivity is a real, physical illness and for some of them this condition seems to be strictly related to Multiple Chemical Sensitivity (MCS). This is what came out of the congress “Mobile Telephony, Wi-Fi, Wi-Max: Are there Health Risks?”, held at Palazzo Marini – Chamber of Deputees in Rome on 14 June 2011. The event, organized by the Association for Environmental and Chronic Toxic Injury (A.M.I.C.A.), was meant to give an overview on the health dangers linked to the use of wireless devices.

Prof. Dominique Belpomme, Oncologist, Professor of the Centre Hospitalier Universitaire Necker-Enfants Malades, Chairman of Research for Anti-Cancer Therapeutics (ARTAC), in his lecture “Diagnostic and Therapeutic Protocols for Electromagnetic Fields Intolerance”, showed the results of a clinical observation on more than 450 patients enrolled from 2008 to 2011. He and his team use a new technique to make the diagnosis to people reporting reactions to electromagnetic fields, a condition that he prefers to define as “Electromagnetic Fields Intolerance” or “EFI Syndrome” rather than “Electromagnetic Hyper-Sensitivity”.

The new technique is the “Pulsed Eco-Doppler” of the brain that combines the eco-doppler with a computer to evaluate brain perfusion. Unlike some other methods, this one is not dangerous and it does not involve any ionizing radiation. The results show that people with Electromagnetic Fields Intolerance have a reduced perfusion in the brain, particularly in the left part of the limbic area of the brain, compared to the control group. This is a very particular area, because it is the “ancient” part of the brain that controls many body functions.

“These results are very important – Belpomme said at the congress – because for the first time we are able to define the Electromagnetic Fields Intolerance as a physical illness based on objective tests”.

His team uses also other tests, such as the dosage of histamine, of protein S100B, and of heat shock proteins hsp70 and hsp27 in the blood. The 70% of the group of patients observed showed a serious reduction of vitamin D, about 1-2% of the patients showed an increase of proteins hsp27 and hsp70, while more than the 40% of the sample had increased histamine, a fact that is fully compatible with a physiological interpretation of this syndrome.

About 10% of the patients had an increased protein S100B, which is a marker for Blood Brain Barrier (BBB) permeability. In one third of the sample, a reduction of melatonin in urine was found, and this can explain symptoms such as fatigue, insomnia and depression in these patients.

These alterations are quite similar to the ones found in patients with Multiple Chemical Sensitivity (MCS), particularly regarding the brain perfusion reduction, the neurogenic inflammation, the oxidative stress increase, and the reduction of the defense mechanism. The fact that EMF induces the opening of the BBB may interfere with the brain protection from toxic chemicals. It is not uncommon, in fact, that patients with EFI Syndrome have MCS symptoms, while many patients with MCS also react to EMF.

The increase of oxidative stress in electrosensitive patients was found also by Dr. Valeria Pacifico, who lectured in Rome about “Metabolic biomarkers of oxidation-reduction imbalance and susceptibility to non-ionizing radiation”. She works in the team of Dr. Chiara De Luca at the Experimental Laboratory BILARA at Istituto Dermopatico of Immaculata in Rome that published several works on the role of oxidative stress in environmental sensitivities. (1, 2)

“To make a diagnosis of this syndrome we need to listen first to patients and we need to verify if the symptoms improve or disappear when they stay away from EMF sources”, Prof. Belpomme explained. In order to demonstrate if the electromagnetic fields were the real cause of the alterations found in these patients, the patients had to repeat the tests before and after a period of avoidance of EMF for three months. The results show that after the period of avoidance the levels tend toward the normal standard.

Given the strong correlation found by six epidemiologic studies on EMF exposure and Alzheimer Disease (AD), Prof. Belpomme believes that any electrosensitive patient with memory dysfunctions should be evaluated also for AD. He stresses the fact that AD is a loss of long term memory while EFI Syndrome often involves the loss of short term memory, but this symptom may be considered as a pre-Alzheimer condition.

Prof. Olle Johansson, Assoc. Prof., The Experimental Dermatology Unit, Department of Neuroscience, Karolinska Institute; Professor, The Royal Institute of Technology, Stockholm, talked in Rome about “The precautionary principle: from Bioinititive to the Seletun consensus”. He dedicated his lecture to people affected by EHS and MCS because “they have a very difficult life”.

He is one of the most dedicated scientists in the promotion of new biologically-based safety guidelines for EMF. He was in Benevento for the ICEMS resolution in 2006, then in London in 2007 for a new resolution, and he was also member of the group of independent scientists that published the famous Bioinitiative Report in 2007, which had strong ecological concern in the political agenda. Thanks to this report, in fact, the European Parliament signed a resolution on September 4, 2008 to state that the actual safety limits for EMF are obsolete and to warn EU governments about the increase of new environmental illnesses such as EHS, MCS and Dental Amalgam Mercury Syndrome.

More recently, Prof. Johansson was part of the group of scientists who prepared the Seletun Consensus, published last February in Reviews on Environmental Health (3). It states that present standards do not protect global human population from electromagnetic fields and all EMF should be reduced now instead of waiting for a definitive proof of danger. It also states that people reporting EHS symptoms should be considered as having a functional disability.

In Sweden, for example, EHS, MCS and fibromyalgia are already classified as functional disabilities. This means that people affected by these conditions are not considered patients, but it’s the environment that creates limitations for them so it’s the environment that has to be changed. This kind of classification represents the full concretization of the UN Convention on the Rights of Persons with Disabilities, signed by governments on March 30, 2007. This convention should be enough to push all governments to find the right accommodation and the best welfare strategies for people with environmental sensitivities, and put an end to discrimination.

Author: Francesca Romana Orlando, journalist and Vice President of A.M.I.C.A.

Literature:

  1. De Luca C. et al., Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes, Toxicology and Applied Pharmacology, YTAAP-11818; No. of pages: 8; 4C.
  2. De Luca C. et al., The Search for Reliable Biomarkers of Disease in Multiple Chemical Sensitivity and Other Environmental Intolerances, Int. J. Environ. Res. Public Health 2011, 8, 2770-2797; doi:10.3390/ijerph8072770
  3. Fragopoulou A ed al., Scientific panel on electromagnetic field health risks: consensus points, recommendations, and rationales, Rev Environ Health. 2010 Oct-Dec; 25(4):307-17.

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The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances

Whilst facing a worldwide fast increase of food and environmental allergies, the medical community is also confronted with another inhomogeneous group of environment-associated disabling conditions, including multiple chemical sensitivity (MCS), fibromyalgia, chronic fatigue syndrome, electric hypersensitivity, amalgam disease and others. These share the features of poly-symptomatic multi-organ cutaneous and systemic manifestations, with postulated inherited/acquired impaired metabolism of chemical/physical/nutritional xenobiotics, triggering adverse reactions at exposure levels far below toxicologically-relevant values, often in the absence of clear-cut allergologic and/or immunologic involvement.

Due to the lack of proven pathogenic mechanisms generating measurable disease biomarkers, these environmental hypersensitivities are generally ignored by sanitary and social systems, as psychogenic or “medically unexplained symptoms”. The uncontrolled application of diagnostic and treatment protocols not corresponding to acceptable levels of validation, safety, and clinical efficacy, to a steadily increasing number of patients demanding assistance, occurs in many countries in the absence of evidence-based guidelines.

De Luca et. al. revised available information supporting the organic nature of these clinical conditions. Following intense research on gene polymorphisms of phase I/II detoxification enzyme genes, so far statistically inconclusive, epigenetic and metabolic factors are under investigation, in particular free radical/antioxidant homeostasis disturbances. The finding of relevant alterations of catalase, glutathione-transferase and peroxidase detoxifying activities significantly correlating with clinical manifestations of MCS, has recently registered some progress towards the identification of reliable biomarkers of disease onset, progression, and treatment outcomes.

Literature:

De Luca C, Raskovic D, Pacifico V, Thai JC, Korkina L., The search for reliable biomarkers of disease in multiple chemical sensitivity and other environmental intolerances, Tissue Engineering & Skin Pathophysiology Laboratory and 2nd Dermatology Division, Dermatological Research Institute (IDI IRCCS), Via Monti di Creta 104, Rome 00167, Italy; Int J Environ Res Public Health. 2011 Jul;8(7):2770-97. Epub 2011 Jul 1.

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Canada: Environmental Sensitivities in Quebec

For those living with Environmental sensitivities, life is very difficult

In Quebec there are 170,000 people who have a medical diagnosis of Environmental Sensitivities Yet for most, their illness goes without proper medical treatments due to the lack of Government and Public Awareness, limited Doctor Training, and the need for a Designated Treatment Centre.

The Environmental Health Association of Québec (ASEQ-EHAQ) is a non-profit, charitable organization founded in 2004. Presently, membership of the group is over 1200. ASEQ-EHAQ’s mission encompasses not only support for people suffering from environmental sensitivities but also provides the community with resources to cope with the disease (education, help line, the latest information about environmental sensitivities and treatment, support meetings, healthy housing, a resource guide, newsletters…) ASEQ-EHAQ also works tirelessly to educate the community at large on the use of ecological strategies to maintain a healthy environment.

Environmental sensitivities is a chronic, disabling condition that is not always visually recognizable. It affects people of all ages – youth and children included. Many symptoms can be identified using published diagnostic guidelines.

Environmental sensitivities sufferers experience physical symptoms such as headaches and fatigue, when exposed to a wide range of chemical substances. Recent research is showing that there is a biological basis for the symptoms noted above. At this time, there is no known cure.

For those living with Environmental sensitivities, life is very difficult especially because awareness in the medical community is extremely limited. The few doctors who are knowledgeable about and treat Environmental sensitivities are stretched beyond capacity. Many patients are dismissed by their family doctors when a diagnosis is made. Others find it impossible to find a physician with the training to care for them. There are no education, treating or research centers in Quebec.

There is an urgent need for information to be made available to the public. People must have a greater understanding about the illness and the challenges faced by those who live with it. Help is also needed at the most basic levels of home and long-term care. Many people with this illness cannot care for themselves or their families. They cannot work and must rely on government support.

See the chart for a breakdown of the affected population in QUEBEC. These numbers exceed that of many other better-known chronic conditions.

It is costing the government both in direct health care costs and economic losses (as sufferers are forced to stop working). It is estimated the combined loss of productivity due to this illness in CANADA (affecting well over a million people) is more than 20 billion dollars annually, the direct medical cost itself over 2 billion dollars. The Quebec figures are proportionately staggering. The provincial government has an important role to play in improving the situation.

ASEQ-EHAQ strives to raise awareness within communities, corporations, governments, educational institutions, the medical community and the general public to prevent further cases of Environmental sensitivities. We will continue to work with all doctors, scientists, health and environmental groups and individuals across Canada to create ties with similar organizations throughout North America and overseas.

Environmental Health Association of Quebec

Contact: Michel Gaudet

Tel: 514.683.5701

office @ aseq-ehaq.ca

www.aseq-ehaq.ca

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Environmental Diseases: THE VULNERABLE MANIFESTO

Another year. One more year. Nothing has changed.

Today, May 12th, I have woken up locked up in the same place and I can still see that:

Society continues to poison me with its toxics, this cruel, unjust society that is so comfortable in its greediness, while it rejects me for not producing and not consuming as healthy bodies do, while the owners of the toxic industries laugh at me and get richer.

They abandon me and say that it is my fault that I live with this illness, as though it was a whim, as though I did not want to make an effort, as though it was something I made up to avoid going to work.

My body, my bed and my walls have become a prison with only my window and my thoughts as company, with no chance of parole in sight.

I am condemned to live in the shadows because I am what society wants to hide. I am part of the narrative that will never make it into the history books.

After years of working hard and paying taxes, I have no rights and I am excluded from the Welfare State. They consider me useless although what I really am is disabled.

My exile is imposed on me by administrations, politicians and doctors, the same ones who promised me they would be there to help me. They have betrayed me when I most needed them. Now they pretend I don’t exist. They act as though I was a bother and they make fun of me while they hide the fact that everyday there are more and more of us.

Although I can barely move, I have decided, once more, to be determined and brave. Visible despite being housebound. Weak and vulnerable but never a coward.

I have decided I will continue to live, to fight, despite my vulnerability. I will not be silenced although they want to shut me up.

This is what I have decided again this year. Once again, because nothing has changed.

I hope that you will do the same. Yes, you who are vulnerable, although you do not realize it. We need to continue to fight without giving up, to shake society’s comfortable thoughts and question how we live as a society. To question this “development” which is killing us slowly. Until those of us who are vulnerable are not defenseless anymore. Until there is justice, respect and tenderness for all.

Authors: No Fun and Liga SFC (CFS/ME League), Spain, May 12, 2011

* May 12th, International Day of Central Sensitivity Syndromes (Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis, Fibromyalgia and Multiple Chemical Sensitivity)

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WHO receives delegation of representatives for the environmentally ill

MCS stakeholders sign petition to the World Health Organization

On May 13, a petition from the WHO delegation of stakeholders from MCS and EMS patients, physicians, scientists, lawyers and journalists in Geneva will be received. The delegation will be welcomed by Dr. Maria Neira, Director General of Public Health and Environment, WHO confirms.

WHO confirmed hearing from MCS organizations

Dr. Neira will receive the relevant documents from the delegation, a bibliography regarding environmental diseases, a list of countries that already have a ICD-10 code for MCS and / or EMS, and some other relevant documents for the meeting. All documents being submitted support the science-based arguments, and finally create a mandatory basis for environmental health conditions worldwide, so that the medical care of patients can be assured.

MCS and EMS organizations sign the WHO petition

The petition, which seeks to ensure that the situation for people, who are chemically sensitive or electro-sensitive, was improved by the Spanish organization „Asquifyde”. The petition was signed by many organizations, researchers, and practitioners from around the world. The hope is that WHO will implement this petition, which would apply a consistent international code of disease (ICD) in all countries worldwide for those with Multiple Chemical Sensitivity (MCS) and electromagnetic sensitivity (EMS). This ICD code is important because it will allow patients’ doctors to give an accurate diagnosis with expected benefits from the health insurance, which already exists for other disabilities and illnesses. The existence of MCS and EMS has already been demonstrated.

In all countries, binding ICD-10 code for MCS and EMS

Currently, Japan (T65.9) and Germany (T78.4) have the ICD-10 code for MCS. Other German-speaking countries like Switzerland, Luxembourg and Austria ,through their Ministry of Health, say that in their countries the ICD-10 code for MCS, T78.4, is valid and can be used as well.

Submission of evidence to the WHO

It is possible to contribute and submit other important documents regarding the scientific aspects of MCS and EMS, to the WHO. During the next few days a PDF may be sent via e-mail to: info@asquifyde.es which is the Spanish organization. All documents received by medical experts and lawyers for environmental law will be organized in terms of their relevance and then selected for submission to the WHO.

Confirmed participation in the WHO hearing

Until May 3rd, 2011 it possible for organizations, academics, lawyers, and doctors to register for consultation with WHO in Geneva. This requires a binding confirmation take place with Asquifyde. The organization will report the final number of participants on May 3rd to Dr. Neira, after which it is appropriate to reserve a space.

WHO press conference after hearing

According to the WHO, a press conference will take place after the hearing. It will be headed by Sonia Miguel Jara and journalists. To fund this important press conference following the WHO hearing, Asquifyde and other MCS and EMS organizations, are asking anyone who is concerned about the environmental concerns of those ill from environmental factors to contribute financial support.

Help the environmentally ill

Scientists estimate that about 15-30% of the general population in industrialized countries suffer with MCS. The number of EMS stakeholders increases by the progressive expansion of mobile networks also. These people are almost without exception, without the help and support, which contradicts the international disability convention and applicable laws. Ignoring and negation of environmental diseases in recent years has led to indescribable suffering and to considerable financial losses to the economy. It is hoped that the leaders at the WHO, will respect the suffering of those patients with MCS and EMS and take seriously the international petition and act according to their stated mission which is to provide assistance to those disabled internationally.

Author: Silvia K. Müller, CSN – Chemical Sensitivity Network, 2 May 2011

Translation: Christi Howarth for CSN

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