Archive for category ‘Hormone Disrupting Chemicals‘

European Commission confirms intentions on BPA

Brussels, 22 November 2010 – The Health and Environment Alliance (HEAL) welcomes a news report that the European Commission has launched discussions on a ban on Bisphenol A in baby bottles.

In an exclusive report in Food Quality News, European Commission is quoted as saying that it wants to introduce a region-wide ban on the use of Bisphenol A (BPA) in baby bottles. (1)

“If this is true, it is a step in the right direction,” says Lisette van Vliet, Toxics Policy Advisor at HEAL. “But this only relates to baby bottles. The ban should be for ALL food packaging for infants under 3 years old – and it should quickly be extended to all food packaging because, if babies during pregnancy are to be protected, consumption by women of child-bearing age should be avoided.”

HEAL was disappointed earlier this month by the outcome of the World Health Organization expert meeting in Ottawa, Canada, 1-5 November 2010 on Bisphenol A. The WHO opinion was that it would be premature to take any action on Bisphenol A on public health grounds. (2)

HEAL board member, André Cicollela, Réseau Environnement Santé (RES) said: “The conclusion is very surprising because it gives the impression that the scientific evidence is not available. This is far from the reality: almost 500 peer-reviewed studies have been published.” (3)

Many of the studies show increased risks for a plethora of health effects from breast and prostate cancer, diabetes and obesity, behavioural and reproductive problems, at doses well below the current ‘tolerable daily intakes’ advised by the US EPA and the European Food Safety Authority. The WHO reasoning is based on a dismissal of the importance of peoples’ daily and continual exposure to this chemical. Moreover, more than 80 studies show that the levels of internal contamination in people are equivalent to levels that produce the mentioned health effects in animal studies. (3)

In September, the European food panel failed to protect EU citizen’s health from plastic component, BPA. (4)

Prior to that HEAL was a signatory to a joint letter sent to EFSA from scientists and organisations across the globe expressed concerns and concluded that. Based on the available scientific studies, reducing levels of human exposure to BPA was necessary.

Contacts:

Lisette van Vliet– Toxics Policy Advisor, Health and Environment Alliance (HEAL):

+32 (0)2 234 3643, mobile: 32 (0)484 614 528, lisette@env-health.org

Diana Smith, Press and Communications, Health and Environment Alliance, Mobile: +33 6 33 2943, Diana@env-health.org

Reference: HEAL,  Press Release, Commission confirms intentions on BPA, November 22, 2010

Literature:

  1. European Commission wants ban on bisphenol A in baby bottles
  2. World Health Organization documentation: Joint FAO/WHO meeting, 1-5 November 2010, Food is a major source of exposure to bisphenol A, 9 November 2010
  3. Press release (in French) on WHO opinion and European Commission position
  4. Press release and letter available at Chemicals Health Monitor

Industry puts a higher priority on selling chemicals than on the health of infants

Feinstein Statement on Obstruction of Efforts to Reach Compromise Agreement on Use of BPA in Baby Products

Washington, DC – U.S. Senator Dianne Feinstein (D-Calif.)  issued the following statement on blocked efforts to offer a compromise amendment to phase out the use of bisphenol A (BPA) in baby bottles and sippy cups.

Following is Senator Feinstein’s statement:

“Unfortunately, the compromise agreement on a BPA amendment to the food safety bill has been blocked. Last evening, an agreement between myself and Senator Enzi was reached, which would have:

  • Banned the use of BPA in baby bottles and sippy cups (largely because infants and children are the most vulnerable to the harmful effects of BPA),
  • Required the FDA to issue a revised safety assessment on BPA by December 1, 2012; and
  • Included a savings clause to allow states to enact their own legislation.

I thank Ranking Member Enzi for his agreement. Unfortunately it has become clear that the American Chemistry Council (ACC) has blocked and obstructed the agreement from being added to the Food Safety Bill currently on the floor. Therefore, I cannot carry out the agreement that was reached.

I regret that the ACC puts the sale of chemicals above the safety of infants and children.

This was a small step forward – a simple move to ban BPA in baby bottles and sippy cups. A simple move to protect children. All it did was ban BPA in baby bottles and sippy cups until the FDA safety assessment count be revised.

There is no benefit from having this harmful chemical in baby bottles and sippy cups for infants. I will not cease in my efforts to remove BPA from products where it can harm human health, and I urge consumers to vote with their pocketbooks by refusing to purchase products that contain BPA. This is especially important when it comes to buying products that will be used by infants or children.

However, I am pleased that seven states have taken initiative to phase out or ban BPA. I also commend the manufacturers and retailers who have wisely begun to phase out BPA from children’s products and search for alternatives. At least 14 major manufacturers either offer some BPA-free alternatives for baby bottles and sippy cups, or completely ban its use.

What I have learned from this experience is that compromise is not possible on this issue. I very much regret that the chemical industry puts a higher priority on selling chemicals than on the health of infants.”

Reference:

Senator Dianne Feinstein, Feinstein Statement on Obstruction of Efforts to Reach Compromise Agreement on Use of BPA in Baby Products, November 17, 2010

Photo: Senator Dianne Feinstein

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Researchers renew call for governmental agencies to identify all products with BPA

New Study Indicates Higher than Predicted Human Exposure to the Toxic Chemical Bisphenol A or BPA

COLUMBIA, Mo. – Researchers have discovered that women, female monkeys and female mice have major similarities when it comes to how bisphenol A (BPA) is metabolized, and they have renewed their call for governmental regulation when it comes to the estrogen-like chemical found in many everyday products.

A study published online in the Sept. 20 NIH journal Environmental Health Perspectives ties rodent data on the health effects of BPA to predictions of human health effects from BPA with the use of everyday household products. The study was authored by researchers at the University of Missouri Division of Biological Sciences, Veterinary Medical Diagnostic Lab (VMDL) and the department of Biomedical Sciences, in collaboration with scientists at the University of California-Davis and Washington State University.

“This study provides convincing evidence that BPA is dangerous to our health at current levels of human exposure,” said Frederick vom Saal, Curators’ professor of biological sciences at the University of Missouri. “The new results clearly demonstrate that rodent data on the health effects of BPA are relevant to predictions regarding the health effects of human exposure to BPA. Further evidence of human harm should not be required for regulatory action to reduce human exposure to BPA.”

BPA is one of the world’s highest production-volume chemicals, with more than 8 billion pounds made per year. It can be found in a wide variety of consumer products, including hard plastic items such as baby bottles and food-storage containers, the plastic lining of food and beverage cans, thermal paper used for receipts, and dental sealants. The findings in the current study suggest that human exposure to BPA is much higher than some prior estimates and is likely to be from many still-unknown sources, indicating the need for governmental agencies to require the chemical industry to identify all products that contain BPA.

Several states, including Connecticut, Massachusetts, Washington, New York and Oregon, have passed bills to reduce exposure to BPA, and similar legislation is pending in the U.S. Congress.

“For years, BPA manufacturers have argued that BPA is safe and have denied the validity of more than 200 studies that showed adverse health effects in animals due to exposure to very low doses of BPA,” said Julia Taylor, lead author and associate research professor at the University of Missouri. “We know that BPA leaches out of products that contain it, and that it acts like estrogen in the body.”

“We’ve assumed we’re getting BPA from the ingestion of contaminated food and beverages,” said co-author Pat Hunt, a professor in the Washington State University School of Molecular Biosciences. “This indicates there must be a lot of other ways in which we’re exposed to this chemical and we’re probably exposed to much higher levels than we have assumed.”

The research team at the University of Missouri includes Taylor, vom Saal and student researcher Bertram Drury in Biological Sciences, as well as Wade Welshons in Biomedical Sciences and George Rottinghaus in the VMDL at MU.

Reference:

University of Missouri, New Study Indicates Higher than Predicted Human Exposure to the Toxic Chemical Bisphenol A or BPA, September 20th, 2010.

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Impact of chemical BPA in dental sealants used in children

Dentists should take precautions to reduce potential absorption of BPA from dental resins

Researchers from Mount Sinai School of Medicine have found that bisphenol A (BPA) released from some plastic resins used in pediatric dentistry is detectable in the saliva after placement in children’s mouths. BPA is a widely used synthetic chemical that has been associated with changes in behavior, prostate and urinary tract development, and early onset of puberty. The findings are published in the current issue of Pediatrics.

Resins containing BPA are commonly used in preventive and restorative oral care. Children often have their teeth sealed with a dental resin containing BPA to prevent cavities, and it is often used for fillings. Led by Philip Landrigan, MD, Dean for Global Health, Professor and Chair of Preventive Medicine, and Director of the Children’s Environmental Health Center at Mount Sinai School of Medicine, the research team conducted a literature review and found that BPA was detectable in saliva for up to three hours after the dental work was completed.

“BPA is commonly used in dental products, and while exposure from dental materials is much less common than from food storage products, we are still concerned,” said Dr. Landrigan. “These dental products are still safe and an effective way to promote good oral health, but dentists should take precautions to reduce potential absorption of this chemical and the negative side effects associated with it.”

Dr. Landrigan’s team reviewed toxicology data over the last 10 years to examine the benefits and potential childhood health risks of using dental materials containing BPA. They determined that dental products contain different derivatives of BPA, and that saliva breaks down the derivative into BPA during the dental procedure and for three hours following it. As a further precaution the authors urge that resins containing BPA not be applied in women during pregnancy.

The authors caution that these results are preliminary, and that data on the absorption of BPA in the body were not available. “Further research is needed to fully grasp the impact of BPA in dental products, and to analyze all dental products that use this chemical,” continued Dr. Landrigan. “However, the overwhelming benefit of these dental resins in oral health outweighs the brief exposure to BPA. Dentists should continue to use these products, but manufacturers should disclose specific information about the chemical structures of these products and search for alternatives.”

To reduce exposure, the authors recommend the use of one BPA derivative called bis-GMA over another, bis-DMA, as bis-GMA seems to pose less risk. They also recommend that dentists rub the surface of the materials with pumice to remove the top liquefied layer of the sealant. Another preventive measure would be to encourage the patient to rinse for 30 seconds immediately following the procedure to prevent saliva from breaking the chemical down into BPA.

Literature:

The Mount Sinai Hospital / Mount Sinai School of Medicine, Mount Sinai researchers analyze impact of chemical BPA in dental sealants used in children, Sept. 10, 2010.

Sperm may be harmed by exposure to BPA, study suggests

More research should focus on BPA and health effects in adults

In one of the first human studies of its kind, researchers have found that urinary concentrations of the controversial chemical Bisphenol A, or BPA, may be related to decreased sperm quality and sperm concentration.

However, the researchers are quick to point out that these results are preliminary and more study is needed. Several studies have documented adverse effects of BPA on semen in rodents, but none are known to have reported similar relationships in humans.

BPA is a common chemical that’s stirred much controversy in the media lately over its safety. Critics say that BPA mimics the body’s own hormones and may lead to negative health effects. BPA is most commonly used to make plastics and epoxy resins used in food and beverage cans, and people are exposed primarily through diet, although other routes are possible. More than 6 billion pounds of BPA are produced annually.

The new study suggests that more research should focus on BPA and health effects in adults, says John Meeker, assistant professor of Environmental Health Sciences at the University of Michigan School of Public Health.

Meeker is the lead author on the study, along with Russ Hauser, the Frederick Lee Hisaw Professor of Reproductive Physiology at Harvard School of Public Health. Colleagues at Massachusetts General Hospital and the U.S. Centers for Disease Control and Prevention also contributed to the research.

“Much of the focus for BPA is on the exposures in utero or in early life, which is of course extremely important, but this suggests exposure may also be a concern for adults,” Meeker said. “Research should focus on impacts of exposure throughout multiple life stages.” Meeker and Hauser recruited 190 men through a fertility clinic. All gave spot urine samples and sperm samples the same day. Subsequently, 78 of the men gave one or two additional urine samples a month apart. Researchers detected BPA in 89 percent of the urine samples.

Researchers measured sperm concentration, sperm motility, sperm shape and DNA damage in the sperm cell.

“We found that if we compare somebody in the top quartile of exposure with the lowest quartile of exposure, sperm concentration was on average about 23 percent lower in men with the highest BPA,” Meeker said.

Results also suggested a 10 percent increase in sperm DNA damage.

The results are consistent with a previous study by Meeker and Hauser suggesting that certain hormones, specifically FSH (follicle-stimulating hormone) and Inhibin B, are elevated or decreased in relation to BPA, respectively, a pattern consistent with low sperm production and development.

Meeker stressed that further study is necessary due to the study’s relatively small sample size and design.

“The study from which these data came is currently in progress,” Hauser said. “With a larger sample size and enhanced study design, we will be able to more definitively investigate this preliminary association in the near future.”

Reference:

University of Michigan, Sperm may be harmed by exposure to BPA, study suggests, ANN ARBOR, Mich., Aug. 3, 2010.

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